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Table 2 Conservation or acceleration in promoter sequences of the nine genes studied in this work, estimated based on the likelihood ratio test of phyloP for the subtree comparing an alternative model (alt_subscale) with a free scale parameter (alt_scale) within the given REV substitution model (null_scale). Positive scores indicate evolutionary conservation, and negative scores denote evolutionary acceleration, as observed in the IGF2, IGFBP2, IGFBP7, and ZFAT promoters

From: Patterns of enrichment and acceleration in evolutionary rates of promoters suggest a role of regulatory regions in cetacean gigantism

Gene

null_scale

alt_scale

alt_subscale

Log-likelihood ratio

score

EGF

0.98697

0.98845

0.91995

0.06824

0.71181

GHSR

0.99969

1.00026

0.97634

0.01678

0.85465

IGF2

1.00693

1.00660

1.01574

0.00836

-0.89709

IGFBP2

0.85126

0.84986

1.11514

0.16139

-0.56994

IGFBP7

0.97794

0.97747

1.03213

0.01757

-0.85131

LCORL

0.99179

0.99239

0.97383

0.01599

0.85809

NCAPG

0.99783

0.99838

0.92715

0.11610

0.62989

PLAG1

1.00465

1.00523

0.97163

0.01838

0.84795

ZFAT

0.99639

0.99606

1.01425

0.01237

-0.87503