Fig. 2

Maximum likelihood (ML) phylogeny of DENV-2. Thirty-two newly sequenced genomes from Managua and León, Nicaragua, are shown in the clade colored magenta (samples from León are denoted by “LLE”). The enlarged tree on the right represents the phylogeny shaded gray in the tree in the upper left-hand corner. Sequences are labeled by ISO country code, sample identifier, and year of isolation. Bootstrap values are shown for each clade. Each black bar on the branches represents a clade-specific non-synonymous mutation