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Fig. 7 | BMC Ecology and Evolution

Fig. 7

From: A model for the dissemination of circulating tumour cell clusters involving platelet recruitment and a plastic switch between cooperative and individual behaviours

Fig. 7

The role of autocrine TGF-β1 signalling in the migration of TGF-β1-induced adherent H2122 cells in the absence of exogenous TGF-β1. Number of TGF-β1-induced adherent H2122 SS cells that migrated to the underside of the insert (per field of view) after the initial treatment with TGF-β1 for 24 h, as well as after an additional 24 h in either the presence of 10 ng/ml TGF-β1, the absence of exogenous TGF-β1, or in the presence of 10 µM TGFβRI inhibitor. Error bars represent standard error, n = 3. Asterisk (*) indicates a significant difference between migrated cells in the absence of exogenous TGF-β1 and the TGFβRI inhibitor (p < 0.05)

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