From: Exploring metazoan evolution through dynamic and holistic changes in protein families and domains
Groups | GO terms | Description | P-value |
---|---|---|---|
Families born at the LCA of metazoans | Â | ||
 | GO:0006355 | regulation of transcription, DNA-dependent | 1.29E-106 |
 | GO:0006836 | neurotransmitter transport | 7.59E-11 |
 | GO:0007275 | multicellular organismal development | 1.25E-09 |
 | GO:0006637 | acyl-CoA metabolic process | 4.33E-08 |
 | GO:0007186 | G-protein coupled receptor protein signaling pathway | 1.35E-07 |
 | GO:0007040 | lysosome organization and biogenesis | 4.78E-06 |
 | GO:0007223 | Wnt receptor signaling pathway, calcium modulating pathway | 4.78E-06 |
 | GO:0030704 | vitelline membrane formation | 6.47E-06 |
 | GO:0006508 | proteolysis | 1.48E-05 |
 | GO:0006094 | gluconeogenesis | 1.90E-05 |
 | GO:0006665 | sphingolipid metabolic process | 3.24E-05 |
 | GO:0007179 | transforming growth factor beta receptor signaling pathway | 3.24E-05 |
 | GO:0006869 | lipid transport | 5.22E-05 |
 | GO:0045449 | regulation of transcription | 9.33E-05 |
 | GO:0006835 | dicarboxylic acid transport | 3.50E-04 |
 | GO:0007600 | sensory perception | 3.50E-04 |
 | GO:0045087 | innate immune response | 8.15E-04 |
 | GO:0007026 | negative regulation of microtubule depolymerization | 9.14E-04 |
Families born at the LCA of nematodes | Â | ||
 | GO:0051085 | chaperone cofactor-dependent protein folding | 9.14E-04 |
 | GO:0007186 | G-protein coupled receptor protein signaling pathway | 3.54E-116 |
 | GO:0016998 | cell wall catabolic process | 7.49E-06 |
 | GO:0005992 | trehalose biosynthetic process | 2.37E-05 |
 | GO:0006812 | cation transport | 2.98E-04 |
Families born at the LCA of arthropods | Â | ||
 | GO:0006030 | chitin metabolic process | 1.08E-22 |
 | GO:0006814 | sodium ion transport | 2.32E-18 |
 | GO:0006950 | response to stress | 2.02E-11 |
 | GO:0007608 | sensory perception of smell | 4.74E-11 |
Families born at the LCA of vertebrates | Â | ||
 | GO:0007186 | G-protein coupled receptor protein signaling pathway | 7.41E-155 |
 | GO:0006955 | immune response | 1.29E-39 |
 | GO:0001558 | regulation of cell growth | 2.57E-10 |
 | GO:0007154 | cell communication | 4.19E-10 |
 | GO:0050909 | sensory perception of taste | 4.88E-10 |
 | GO:0045087 | innate immune response | 1.04E-09 |
 | GO:0015671 | oxygen transport | 7.68E-09 |
 | GO:0048468 | cell development | 1.03E-08 |
 | GO:0006691 | leukotriene metabolic process | 7.08E-08 |
 | GO:0042981 | regulation of apoptosis | 1.99E-07 |
 | GO:0019882 | antigen processing and presentation | 3.04E-07 |
 | GO:0009395 | phospholipid catabolic process | 3.60E-06 |
 | GO:0006915 | apoptosis | 5.43E-06 |
 | GO:0016049 | cell growth | 2.51E-05 |
 | GO:0006486 | protein amino acid glycosylation | 3.09E-05 |
 | GO:0006952 | defense response | 5.80E-05 |
 | GO:0006071 | glycerol metabolic process | 8.96E-05 |
 | GO:0009607 | response to biotic stimulus | 2.40E-04 |
 | GO:0030178 | negative regulation of Wnt receptor signaling pathway | 2.54E-04 |
 | GO:0043065 | positive regulation of apoptosis | 2.54E-04 |