Figure 1

Alignment of human lysozyme-like proteins. Amino acid sequences of predicted human lysozyme-like proteins are aligned. The number +1 identifies the N-terminal amino acid of the mature protein and the signal peptides are shown in italics, based upon homology with lysozyme and lactalbumin. The number symbols (#) identify the active site residues (positions Glu-35 and Asp-52 of the mature protein sequence) of lysozyme c. The solid black triangles above the sequences indicate the positions in the coding sequence that are interrupted by introns in the genes. Asterisks below the sequences identify residues that are perfectly conserved among the sequences, while the symbols ":" and "." indicate conserved and semi-conserved residues, respectively.