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Fig. 2 | BMC Ecology and Evolution

Fig. 2

From: Divergent patterns of selection on metabolite levels and gene expression

Fig. 2

Metabolite QTL Mapping. A The QTL mapping process for this study: 1) Histograms showing the lanosterol and log(DCD/Squalene levels) for the F2 segregants. 2) lanosterol levels for F2 segregants, split based on their allele (BY or RM) at the peak marker variant for the Chr 12/HAP1 QTL. Pearson r2 for the marker correlation with lanosterol level scaled to the mean of the segregant levels shown. 3) LOD score plot for the first round of QTL mapping for lanosterol levels. 4) LOD score plot for the second round of QTL mapping after regressing out the QTL mapped in the first round. B Pearson correlations between the peak marker for each QTL and metabolite levels and ratios. Separate heatmaps are shown for QTL mapped using metabolite levels and metabolite ratios. Red indicates segregants with the BY allele have higher levels of the metabolite or ratio, and blue indicates segregants with the RM allele have higher levels of the metabolite or ratio. QTLs which are significant for a given metabolite level or ratio are marked with * in the cell matching the row of the QTL and the column of the metabolite or ratio which it affects

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