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Table 3 A number of genotype-specific genes mutated in the course of evolution exhibiting genetic interactions (GIs) with primarily deleted COG7, NUP133 or MSH2, respectively

From: Genetic interaction network has a very limited impact on the evolutionary trajectories in continuous culture-grown populations of yeast

Primarily deleted gene

Evolved strain

Genes exhibiting genetic interaction/s with primarily deleted gene

Mutated genes

Lenienta

Stringent confidenceb

COG7

cog7Δ

0

0

2

cog7Δ msh2Δ

5 (1)

0

51 (8)

NUP133

nup133Δ

0

0

4

nup133Δ msh2Δ

8 (4)

3 (1)

51 (15)

MSH2

cog7Δ msh2Δ

6

1

51 (8)

nup133Δ msh2Δ

3

2

51 (15)

msh2Δ

0

0

10 (3)

  1. a(P < 0.05)
  2. b(P < 0.05 and GIS > 0.16 or < -0.12)