Skip to main content

Table 1 Selection signature at the MHC class I exon 2 and exon 3 in passerine and non-passerine birds

From: The strength of selection is consistent across both domains of the MHC class I peptide-binding groove in birds

Exon

Length (bp)

Lineage

No. species (families)

No. residues

dN/dS ratio

Pervasive positive selection (FUBAR/FEL)

Episodic positive selection (MEME)

Negative selection (FUBAR/FEL)

All residues

Positively selected residues

2

264

Non-passerines

63 (28)

6/7

20 (13)

32/32

0.54

2.04

  

Passerines

57 (18)

9/10

20 (11)

26/25

0.64

2.83

  

All

120 (46)

11/12

27 (16)

37/37

0.54

2.05

3

276

Non-passerines

63 (28)

4/6

19 (13)

37/39

0.67

2.59

  

Passerines

57 (18)

12/13

30 (17)

25/25

0.64

2.97

  

All

120 (46)

7/10

32 (22)

35/38

0.74

2.90

  1. The numbers of residues under pervasive positive and negative selection were inferred with FUBAR and FEL approaches, while the number of residues under episodic positive selection was inferred with MEME approach. The number of residues under episodic positive selection (MEME) that were not recognized as under pervasive positive selection (FUBAR or FEL) was given in parentheses. Nucleotide substitution rates (dN/dS ratio) were inferred for all residues and for 20 most positively selected residues