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Table 1 Simulation design.The table shows the treatments used in each of two simulation series, ASHIFT and RFREQ. Root frequencies indicates whether initial codon frequencies were drawn independently from the mutation-selection models applied to the tree. Balance indicates the simulated tree balace condition: BAL = balanced, BDP = birth-death balance, IMB = imbalanced

From: Inferring the number and position of changes in selective regime in a non-equilibrium mutation-selection framework

Series

Selective shifts

Root frequencies?

Taxa

Codons

Balance

Birth rate

Replicates per block

ASHIFT

1

No

10,20

300,600,900

BDP

0.5

20

0

No

10,20

300,600,900

BDP

0.5

20

RFREQ

0

Yes

20

300

BAL, BDP, IMB

0.1, 0.5, 2.0, 5.0, 10.0

10