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Table 2 False Positive Rates (FPR) for different conditions and posterior probability thresholds under model M1 and M2

From: Detecting consistent patterns of directional adaptation using differential selection codon models

 

M1

M2

Threshold

Mean number of FP

FPR

Mean number of FP

FPR

Condition 1 (within-patients)

 >0.55

1843.7

20.8

1845.8

20.8

 >0.60

1112.7

12.6

1166.8

13.2

 >0.65

684.9

7.7

737.8

8.3

 >0.70

316.9

3.6

334.5

3.8

 >0.75

173.1

2.0

181.8

2.1

 >0.80

81.8

0.9

86.5

1.0

 >0.85

26.0

0.3

31.7

0.4

 >0.90

7.1

0.1

4.6

0.1

 >0.95

0.75

0.01

0.1

0.0

Condition 2 (HLA-B57+)

 >0.55

1004.1

11.3

957

10.8

 >0.60

456.3

5.15

471

5.3

 >0.65

229

2.58

237.1

2.7

 >0.70

88.9

1

78.7

0.9

 >0.75

31.3

0.3

27.3

0.3

 >0.80

12.9

0.15

8.4

0.1

 >0.85

3.8

0.04

1.6

0.02

 >0.90

0.4

0

0.05

0

 >0.95

0

0

0

0

Condition 3 (HLA-B35+)

 >0.55

1245.1

14

1226.5

13.8

 >0.60

632.4

7.1

683

7.7

 >0.65

345.6

3.9

385.3

4.3

 >0.70

141.4

1.6

148.1

1.7

 >0.75

58.6

0.7

64.4

0.73

 >0.80

25.3

0.3

23.1

0.3

 >0.85

7.7

0.1

6.5

0.07

 >0.90

1.2

0.01

0.9

0.01

 >0.95

0

0

0

0