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Table 1 Results of likelihood ratio tests for positive selection in AMBN

From: Evolutionary analysis of selective constraints identifies ameloblastin (AMBN) as a potential candidate for amelogenesis imperfecta

Models

Hypotheses

LRT

 

Null hypothesis

Alternative hypothesis

−2ΔLnL (df)

p-value

Sites or branches

Site Models

    

Sites under M8 (BEB)

53-taxa data set

M7: beta

M8: beta&ω

42.77 (2)

p < 0.001

135 (ω = 1.49 ± 0.06; PP = 0.99)

328 (ω = 1.50 ± 0.04; PP = 1.00)

360 (ω = 1.48 ± 0.12; PP = 0.96)

375 (ω = 1.49 ± 0.06; PP = 0.99)

394 (ω = 1.48 ± 0.11; PP = 0.97)

Branch Models

    

Branches

53-taxa data set

M0: One-ratio model

M2ω: 2-ratio model

29.89 (1)

p < 0.001

Background (ω = 0.44), Catarrhines (ω = 1.32)

 

M0: One-ratio model

M5ω: 5-ratio model

52.16 (4)

p < 0.001

Background (ω = 0.43), Catarrhines (ω = 1.32), Elephant (ω = 0.73), Elephant shrew (ω = 0.75), Aye aye (ω = 1.13)

56-taxa data set

M0: One-ratio model

M2ω: 2-ratio model

18.11 (1)

p < 0.001

Background (ω = 0.45), Catarrhines (ω = 1.11)

 

M0: One-ratio model

M4ω: 4-ratio model

19.73 (3)

p < 0.001

Background (ω = 0.45), Armadillo (ω = 0.67), Sloth (ω = 1.10), Aardvark (ω = 0.76)

 

M0: One-ratio model

M5ω: 5-ratio model

39.62 (4)

p < 0.001

Background (ω = 0.44), Catarrhines (ω = 1.11), Armadillo (ω = 0.67), Sloth (ω = 1.10), Aardvark (ω = 0.76)

 

M0: One-ratio model

M8ω: 8-ratio model

58.14 (7)

p < 0.001

Background (ω = 0.42), Catarrhines (ω = 1.11), Armadillo (ω = 0.68), Sloth (ω = 1.10), Aardvark (ω = 0.76), Elephant (ω = 0.68), Elephant shrew (ω = 0.76), Aye aye (ω = 1.07)

  1. BEB Bayes Empirical Bayes, PP Posterior Probability