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Table 2 Summary of the Phylogenetic Analysis of Gene Families

From: An insight into the phylogenetic history of HOX linked gene families in vertebrates

Family Name Hsa2 Hsa7/3* Hsa12 Hsa17 Consistency with HOX Phylogeny Topology
ERBB ERBB4 EGFR ERBB3 ERBB2 - (((17, 7)2)12)
97,98
Collagen COL3A1
COL5A2
COL1A2 COL2A1 COL1A1 - ((((12,17)7)2)2)
93,92,83
IGFBP IGFBP2
IGFBP5
IGFBP1
IGFBP3
IGFBP6 IGFBP4 - ((17, 7)2)
((7, 2)12)99,91
INTB ITGB6 ITGB5* ITGB7 ITGB3 - (((3, 17)2)12)
98,99
MYL MYL1 - MYL6 MYL4 - ((17, 2)12)
87
SP Sp3 Sp4 Sp1 Sp2 Yes (((12,2)7)17)
98,89
ZNFN1A ZNFN1A2 ZNFN1A1 ZNFN1A4 ZNFN1A3 - (((7,17)2)12)
94,90
INHB INHBB INHBA INHBC
INHBE
- - ((7,2)12)
93
SLC4A SLC4A3 SLC4A2 - SLC4A1 - ((7,2)17)
85
GLI GLI2 GLI3 GLI1 - - ((7,2)12)
99
HH IHH SHH DHH   - ((7,2)12)
97
  1. For each gene family the chromosomal location and topologies (in the Newick format) of those genes are given, which arose through duplications after the invertebrates-vertebrates split and before the tetrapods-fishes divergence. The percentage bootstrap support of the internal branches is given below each relevant topology.