Figure 3From: Evolution of major histocompatibility complex class I and class II genes in the brown bearPhylogenetic tree constructed for 189 bp long fragment of second exon of DRB and DQB genes in the brown bear. Bayesian posterior probabilities above 70% are shown above branches. Alleles marked with “S” – are present in the southern Scandinavian population, marked with “N” are present in the northern Scandinavian population, ”J” – in Japan , “Si” - in Siberia, “A” – in Alaska [36]. Alleles marked with filled circle are expressed. The other sequences used to generate the tree are: Ailuropoda melanoleuca: Aime-DQB1*01 (GQ496182.1), Aime-DQB1*02 (GQ496183.1), Aime-DQB2*01 (GQ496188.1), Aime-DRB*01 (AY895155.1), Aime-DRB*02 (AY895156.1), Aime-DRB*03 (AY895157.1), Aime-DRB3*01 (GQ496165.1), Aime-DRB3*02 (GQ496166.1); Ursus thibetanus japonicus: Urth-DQB*01 (AB473936.1), Urth-DRB*01 (AB490478.1), Urth-DRB*02 (AB490479.1); Ursus americanus: Uram-DRB*01 (AB490480.1), Uram-DRB*02 (AB490481.1), Uram-DRB*03 (AB490482.1); Ursus maritimus: Urma-DRB*01 (AB490476.1), Urma-DRB*02 (AB490477.1); Tremarctos ornatus: Tror-DRB*01 (AB490489.1), Tror-DRB*02 (AB490490.1); Melursus ursinus: Urur-DRB*01 (AB490485.1), Urur-DRB*02 (AB490486.1), Urur-DRB*03 (AB490487.1), Urur-DRB*04 (AB490488.1); Helarctos malayanus: Urml-DRB*01 (AB490483.1), Urml-DRB*02 (AB490484.1); Canis lupus: DLA-DQB1*22 (AF113704.1), DLA-DQB1*23 (AF113705.1), DLA-DRB1*14 (U44779.1), DLA-DRB1*17 (U44780.1). Monodelphis domestica sequence: Modo-DAB1 (NM_001032991.1) was used to root the tree.Back to article page