Phylogenomic analyses of malaria parasites and evolution of their exported proteins

Table 1 Molecular phylogenetic analyses attempting to resolve the relationships among malaria parasites.

Reference	Gene*	Outgroup taxa	Number of ingroup taxa	Laverania + avian malaria parasites
Waters et al. 1991 [53]	SSU rRNA	Acanthamoeba castellani	10	Yes
Escalante and Ayala 1994 [3]	SSU rRNA	Theileria annulata Babesia bovis Sarcocystis fusiformis	11	No
Escalante and Ayala 1995 [56]	SSU rRNA	Colpidium campylum Euplotes aediculatus Glaucoma chattoni Opisthonecta henneguyi Paramecium tetraurelia	5	Yes
Qari et al. 1996 [68]	SSU rRNA	Toxoplasma gondii, Paramecium tetraurelia	13	No
Escalante et al. 1998 [69]	Cyt b	Toxoplasma gondii	17	No
Rathore et al. 2001 [70]	SSU rRNA	Toxoplasma gondii	8	Yes
	Cyt b	Toxoplasma gondii	8	No
	ClpC	Toxoplasma gondii	9	No
Perkins and Schall 2002 [58]	Cyt b	Theileria annulata Leucocytozoon dubreuli Leucocytozoon simondi	52	No
Kissinger et al. 2002 [57]	SSU rRNA	Theileria annulata Babesia equis	10	Yes
Leclerc et al. 2004 [59]	SSU rRNA	Toxoplasma gondii Sarcocystis fusiformis Babesia bovis	21	No
Roy and Irimia 2008 [60]	SSU rRNA	Leucocytozoon caulleryi Leucocytozoon sabrazesi	18	No
Martinsen et al. 2008 [61]	Cyt b, Cox I, ClpC, ASL (concatenated)	Leucocytozoon spp.	57	No
Ollomo et al. 2009 [4]	Cyt b, Cox I, Cox III (concatenated)	Leucocytozoon caulleryi	17	No
Krief et al. 2010 [7]	Dhfr-ts, Msp2 (concatenated)	Leucocytozoon sabrazesi	42	No
Silva et al. 2010 [53]	29 proteins (concatenated)	Theileria annulata Theileria annulata	8	No

Note that only analyses are listed that included non-Plasmodium species as an outgroup taxa
*Abbreviations: SSU rRNA, 18S small subunit ribosomal RNA; Cyt b, cytochrome b; ClpC, caseinolytic protease C; Cox I and III, cytochrome oxidase I and III; ASL, adenylosuccinate lyase; Dhfr-ts, dihydrofolate reductase-thymidylate synthase; Msp2, merozoite surface protein 2.

ISSN: 2730-7182